Scoring methods in MALDI peptide mass fingerprinting: ChemScore, and the ChemApplex program
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چکیده
منابع مشابه
Scoring methods in MALDI peptide mass fingerprinting: ChemScore, and the ChemApplex program.
No universally accepted score is currently available to determine when a matrix-assisted laser desorption ionization (MALDI) peptide mass fingerprint (PMF) experiment has been successfully carried out. We describe a software program (ChemApplex) based on a calculated parameter (Combined Protein Score) that takes into account (1) peak intensity, (2) the mass accuracy of the match, and (3) ChemSc...
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Protein identification by mass spectrometry (MS) is an important technique in proteomics. By searching an MS spectrum against a given protein database, the most matched proteins are sorted using a scoring function and the top one is often considered the correctly identified protein. Peptide mass fingerprinting (PMF) is one of the major methods for protein identification using MS technology. It ...
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ژورنال
عنوان ژورنال: Journal of the American Society for Mass Spectrometry
سال: 2002
ISSN: 1044-0305,1879-1123
DOI: 10.1016/s1044-0305(01)00320-8